Colin A. Leech: search on Z-Library

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1

New Insights into Beta-Cell GLP-1 Receptor and cAMP Signaling

Tomas, Alejandra, Jones, Ben, Leech, Colin

Journal:

Journal of Molecular Biology

Year:

2019

Language:

english

File:

PDF, 1013 KB

english, 2019

2

Reflecting on RFT and the Reticulating Strategy: a Response to Villatte, Villatte, and Hayes

Barnes-Holmes, Yvonne, Kavanagh, Deirdre, Barnes-Holmes, Dermot, Finn, Martin, Harte, Colin, Leech, Aileen, McEnteggart, Ciara

Journal:

The Psychological Record

Year:

2018

Language:

english

File:

PDF, 357 KB

english, 2018

3

Non-conventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP

Chepurny, Oleg G., Matsoukas, Minos-Timotheos, Liapakis, George, Leech, Colin A., Milliken, Brandon T., Doyle, Robert P., Holz, George G.

Journal:

Journal of Biological Chemistry

Year:

2019

Language:

english

File:

PDF, 7.42 MB

english, 2019

4

Biochemical Characterization of RAR1 Cysteine- and Histidine-Rich Domains (CHORDs): A Novel Class of Zinc-Dependent Protein−Protein Interaction Modules †

Heise, Charles T., Le Duff, Cécile S., Boter, Marta, Casais, Catarina, Airey, Joanne E., Leech, Andrew P., Amigues, Béatrice, Guerois, Raphaël, Moore, Geoffrey R., Shirasu, Ken, Kleanthous, Colin

Journal:

Year:

2007

Language:

english

File:

PDF, 436 KB

english, 2007

5

Review: Mastering the Clinical Conversation: Language as Intervention, Villatte, M., Villatte, J. L., & Hayes, S. C. (2015). New York, NY: The Guilford Press

Barnes-Holmes, Yvonne, Kavanagh, Deirdre, Barnes-Holmes, Dermot, Finn, Martin, Harte, Colin, Leech, Aileen, McEnteggart, Ciara

Journal:

The Psychological Record

Year:

2017

Language:

english

File:

PDF, 252 KB

english, 2017

6

Correction: Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP.

Chepurny, Oleg G., Matsuokas, Minos-Timotheos, Liapakis, George, Leech, Colin A., Milliken, Brandon T., Doyle, Robert P., Holz, George G.

Journal:

Journal of Biological Chemistry

Year:

2019

Language:

english

File:

PDF, 504 KB

english, 2019

7

GPR119 agonist AS1269574 activates TRPA1 cation channels to stimulate GLP-1 secretion

Chepurny, Oleg G., Holz, George G., Roe, Michael W., Leech, Colin A.

Journal:

Molecular Endocrinology

Year:

2016

Language:

english

File:

PDF, 3.19 MB

english, 2016

8

TPR-Mediated Self-Association of Plant SGT1 †

Nyarko, Afua, Mosbahi, Khédidja, Rowe, Arthur J., Leech, Andrew, Boter, Marta, Shirasu, Ken, Kleanthous, Colin

Journal:

Year:

2007

Language:

english

File:

PDF, 441 KB

english, 2007

9

Identification of a novel inactivating R465Q mutation of the calcium-sensing receptor

Colin Leech, Peter Lohse, Violeta Stanojevic, Andreas Lechner, Burkhard Göke, Christine Spitzweg

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 379 KB

english, 2006

10

Interplay between ER Ca2+ Binding Proteins, STIM1 and STIM2, Is Required for Store-Operated Ca2+ Entry

Nelson, Heather, Leech, Colin, Kopp, Richard, Roe, Michael

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 5.19 MB

english, 2018

11

Expression of cAMP-Regulated Guanine Nucleotide Exchange Factors in Pancreatic β-Cells

Colin A. Leech, George G. Holz, Oleg Chepurny, Joel F. Habener

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 76 KB

english, 2000

12

A crystallographic, EPR and theoretical study of the Jahn?Teller distortion in [CuTp2] (Tp? = tris{pyrazol-1-yl}hydridoborate)

Kilner, Colin A., McInnes, Eric J. L., Leech, Michael A., Beddard, Godfrey S., Howard, Judith A. K., Mabbs, Frank E., Collison, David, Bridgeman, Adam J., Halcrow, Malcolm A.

Journal:

Dalton Transactions

Year:

2004

Language:

english

File:

PDF, 303 KB

english, 2004

13

Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets

Veluthakal, Rajakrishnan, Chepurny, Oleg G., Leech, Colin A., Schwede, Frank, Holz, George G., Thurmond, Debbie C.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.18 MB

english, 2018

14

Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes

Parth Narendran, Alistair J. Williams, Kathryn Elsegood, Nicola J. Leech, Dr. Colin M. Dayan

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2003

Language:

english

File:

PDF, 129 KB

english, 2003

15

Dendritic cell-based assays, but not mannosylation of antigen, improves detection of T-cell responses to proinsulin in type 1 diabetes

Parth Narendran, Kathryn Elsegood, Nicola J. Leech, Wallace M. Macindoe, Geert-Jan Boons, Colin M. Dayan

Journal:

Year:

2004

Language:

english

File:

PDF, 166 KB

english, 2004

16

Leptin-stimulated K ATP channel trafficking

Holz, George G, Chepurny, Oleg G, Leech, Colin A

Journal:

Year:

2013

Language:

english

File:

PDF, 303 KB

english, 2013

17

Dendritic Cell-Based Proliferative Assays of Peripheral T Cell Responses to Tetanus Toxoid

PARTH NARENDRAN, KATHRYN ELSEGOOD, NICOLA J. LEECH, COLIN M. DAYAN

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 1.16 MB

english, 2002

18

A Permissive Role for Protein Kinase a in Support of Epac Agonist-Stimulated Human Islet Insulin Secretion

Holz, George G., Chepurny, Oleg G., Leech, Colin A., Dzhura, Igor, Kelley, Grant G., Roe, Michael W., Dzhura, Elvira, Li, Xiangquan, Schwede, Frank, Genieser, Hans-G

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 63 KB

english, 2010

19

IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation

Takatani, Tomozumi, Shirakawa, Jun, Roe, Michael W., Leech, Colin A., Maier, Bernhard F., Mirmira, Raghavendra G., Kulkarni, Rohit N.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.40 MB

english, 2016

20

Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter

Andreas Lechner, Colin A Leech, Elizabeth J Abraham, Anna L Nolan, Joel F Habener

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

21

Phospholipase C-Epsilon Couples cAMP Production and Epac2 Activation to the Facilitation of Calcium-Induced Calcium Release (CICR) in Pancreatic Beta Cells

Holz, George G., Dzhura, Igor, Chepurny, Oleg, Leech, Colin A., Dzhura, Elvira, Afshari, Parisa, Kelley, Grant G., Roe, Michael W., Rindler, Michael J., Xu, Xin, Lu, Youming, Malik, Sundeep, Smrcka, A

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 81 KB

english, 2011

22

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans

Dzhura, Igor, Chepurny, Oleg G., Leech, Colin A., Roe, Michael W., Dzhura, Elvira, Xu, Xin, Lu, Youming, Schwede, Frank, Genieser, Hans-G., Smrcka, Alan V., Holz, George G.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.10 MB

english, 2011

23

Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors

Chepurny, Oleg G., Bonaccorso, Ron L., Leech, Colin A., Wöllert, Torsten, Langford, George M., Schwede, Frank, Roth, Christian L., Doyle, Robert P., Holz, George G.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 7.51 MB

english, 2018

24

α7 Nicotinic Acetylcholine Receptor Regulates the Function and Viability of L Cells

Wang, Dawei, Meng, Qinghe, Leech, Colin A, Yepuri, Natesh, Zhang, Linlin, Holz, George G, Wang, Chunting, Cooney, Robert N

Journal:

Year:

2018

Language:

english

File:

PDF, 1.03 MB

english, 2018

25

Expression of Adenylyl Cyclase Subtypes in Pancreatic β-Cells

Colin A. Leech, Maurice A. Castonguay, Joel F. Habener

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 41 KB

english, 1999

26

Controversies in the management of Graves' disease

Nicky J. Leech, Colin M. Dayan

Journal:

Clinical Endocrinology

Year:

1998

Language:

english

File:

PDF, 127 KB

english, 1998

27

Huntington's Disease of the Endocrine Pancreas: Insulin Deficiency and Diabetes Mellitus due to Impaired Insulin Gene Expression

Ole A. Andreassen, Alpaslan Dedeoglu, Violeta Stanojevic, Duncan B. Hughes, Susan E. Browne, Colin A. Leech, Robert J. Ferrante, Joel F. Habener, M.Flint Beal, Melissa K. Thomas

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 363 KB

english, 2002

28

Synthesis, Characterization and Pharmacodynamics of Vitamin-B 12 -Conjugated Glucagon-Like Peptide-1

Clardy-James, Susan, Chepurny, Oleg G., Leech, Colin A., Holz, George G., Doyle, Robert P.

Journal:

Year:

2013

Language:

english

File:

PDF, 352 KB

english, 2013

29

Facilitation of β-cell K ATP channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac

Leech, Colin A., Dzhura, Igor, Chepurny, Oleg G., Schwede, Frank, Genieser, Hans-G., Holz, George G.

Journal:

Year:

2010

Language:

english

File:

PDF, 964 KB

english, 2010

30

Antiretroviral drug resistance among HIV-1 infected children failing treatment

Jane Mullen, Susan Leech, Siobhan O'Shea, Ian L. Chrystie, Gillian du Mont, Colin Ball, Michael Sharland, Fiona Cottam, Mark Zuckerman, Philip Rice, Philippa Easterbrook

Journal:

Journal of Medical Virology

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

31

Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells

Guoxin Kang, Colin A. Leech, Oleg G. Chepurny, William A. Coetzee, George G. Holz

Journal:

The Journal of Physiology

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

32

Heterologous Overexpression and Purification of Cytochrome c ‘ from Rhodobacter capsulatus and a Mutant (K42E) in the Dimerization Region. Mutation Does Not Alter Oligomerization but Impacts the Heme Iron Spin State and Nitric Oxide Binding Properties †

Huston, Wilhelmina M., Andrew, Colin R., Servid, Amy E., McKay, Alison L., Leech, Andrew P., Butler, Clive S., Moir, James W. B.

Journal:

Year:

2006

Language:

english

File:

PDF, 130 KB

english, 2006

33

Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion

Schwede, Frank, Chepurny, Oleg G., Kaufholz, Melanie, Bertinetti, Daniela, Leech, Colin A., Cabrera, Over, Zhu, Yingmin, Mei, Fang, Cheng, Xiaodong, Manning Fox, Jocelyn E., MacDonald, Patrick E., Gen

Journal:

Molecular Endocrinology

Year:

2015

Language:

english

File:

PDF, 945 KB

english, 2015

34

Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2’-O-Me-cAMP-AM

Kelley, Grant G., Chepurny, Oleg G., Schwede, Frank, Genieser, Hans-G., Leech, Colin A., Roe, Michael W., Li, Xiangquan, Dzhura, Igor, Dzhura, Elvira, Afshari, Parisa, Holz, George G.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.55 MB

english, 2009

35

Insulinotropic toxins as molecular probes for analysis of glucagon-likepeptide-1 receptor-mediated signal transduction in pancreatic β-cells

George G Holz, Colin A Leech, Joel F Habener

Journal:

Year:

2000

Language:

english

File:

PDF, 277 KB

english, 2000

36

A crystallographic and EPR study of the fluxional Cu(ii) ion in [CuL2][BF4]2 (L = 2,6-dipyrazol-1-ylpyridine)

Solanki, Nayan K., Leech, Michael A., McInnes, Eric J. L., Mabbs, Frank E., Howard, Judith A. K., Kilner, Colin A., Rawson, Jeremy M., Halcrow, Malcolm A.

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

2002

Language:

english

File:

PDF, 163 KB

english, 2002

37

Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag

Chepurny, Oleg G., Bertinetti, Daniela, Diskar, Mandy, Leech, Colin A., Afshari, Parisa, Tsalkova, Tamara, Cheng, Xiaodong, Schwede, Frank, Genieser, Hans-G., Herberg, Friedrich W., Holz, George G.

Journal:

Molecular Endocrinology

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

38

Consequences of Inducing Intrinsic Disorder in a High-Affinity Protein–Protein Interaction

Papadakos, Grigorios, Sharma, Amit, Lancaster, Lorna E., Bowen, Rebecca, Kaminska, Renata, Leech, Andrew P., Walker, Daniel, Redfield, Christina, Kleanthous, Colin

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 463 KB

english, 2015

39

Publisher Correction: Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors

Chepurny, Oleg G., Bonaccorso, Ron L., Leech, Colin A., Wöllert, Torsten, Langford, George M., Schwede, Frank, Roth, Christian L., Doyle, Robert P., Holz, George G.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 660 KB

english, 2018

40

Cytosolic adenylate kinases regulate K-ATP channel activity in human β-cells

Violeta Stanojevic, Joel F. Habener, George G. Holz, Colin A. Leech

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 268 KB

english, 2008

41

[Vitamins & Hormones] Incretins and Insulin Secretion Volume 84 || Epac2-Dependent Rap1 Activation and the Control of Islet Insulin Secretion by Glucagon-Like Peptide-1

Leech, Colin A.

Year:

2010

Language:

english

File:

PDF, 448 KB

english, 2010

42

New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice

Holz, George G., Leech, Colin A., Chepurny, Oleg G.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 732 KB

english, 2014

43

Regulation of Glucagon-Like Peptide-1 Receptor and Calcium-Sensing Receptor Signaling by l -Histidine

Leech, Colin A., Habener, Joel F.

Journal:

Year:

2003

Language:

english

File:

PDF, 249 KB

english, 2003

44

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells

Colin A. Leech, Igor Dzhura, Oleg G. Chepurny, Guoxin Kang, Frank Schwede, Hans-G. Genieser, George G. Holz

Journal:

Progress in Biophysics and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 904 KB

english, 2011

45

Leptin Suppression of Insulin Secretion and Gene Expression in Human Pancreatic Islets: Implications for the Development of Adipogenic Diabetes Mellitus 1

Seufert, Jochen, Kieffer, Timothy J., Leech, Colin A., Holz, George G., Moritz, Wolfgang, Ricordi, Camillo, Habener, Joel F.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1999

Language:

english

File:

PDF, 621 KB

english, 1999

46

Signal Transduction of PACAP and GLP-1 in Pancreatic β Cells

COLIN A. LEECH, GEORGE G. HOLZ, JOEL F. HABENER

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 674 KB

english, 1996

47

Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy

Chepurny, Oleg G., Leech, Colin A., Tomanik, Martin, DiPoto, Maria C., Li, Hui, Han, Xinping, Meng, Qinghe, Cooney, Robert N., Wu, Jimmy, Holz, George G.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.69 MB

english, 2016

48

[Methods in Cell Biology] A Practical Guide to the Study of Calcium in Living Cells Volume 40 || Application of Patch Clamp Methods to the Study of Calcium Currents and Calcium Channels

Leech, Colin A.

Year:

1994

Language:

english

File:

PDF, 1.06 MB

english, 1994

49

Back Cover: Synthesis, Characterization and Pharmacodynamics of Vitamin-B 12 -Conjugated Glucagon-Like Peptide-1 (ChemMedChem 4/2013)

Clardy-James, Susan, Chepurny, Oleg G., Leech, Colin A., Holz, George G., Doyle, Robert P.

Journal:

Year:

2013

File:

PDF, 1.49 MB

2013

50

Regulated Expression of Adenosine Triphosphate-Sensitive Potassium Channel Subunits in Pancreatic β-Cells 1

Moritz, Wolfgang, Leech, Colin A., Ferrer, Jorge, Habener, Joel F.

Journal:

Year:

2001

Language:

english

File:

PDF, 446 KB

english, 2001

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